SAFETY AND EFFICACY OF N-ACETYLCYSTEINE IN HOSPITALIZED PATIENTS WITH HIV-ASSOCIATED TUBERCULOSIS: AN OPEN-LABEL, RANDOMIZED, PHASE II TRIAL (RIPENACTB STUDY).

Despite the availability of effective antimicrobials, tuberculosis (TB) is still a serious health threat.Mortality is even higher in people living with HIV who are diagnosed with TB.New therapies are needed to shorten the time required to cure TB and decrease fatality rates in this population.N-acetylcysteine (NAC) is a glutathione precursor and ha

Background: HIV infections are generally asymptomatic, leading to undetected infections and late-stage diagnoses.There are a lack of acceptable testing strategies for routine opt-out HIV screening.Our aim was to evaluate and compare the diagnostic yield of routine opt-out HIV testing strategies in two out-patient settings in a low HIV prevalence co

GLOSSY LIPSTICK NUDE RAIN #504 Aujeszky’s disease is caused by Suid alphaherpesvirus 1, and its main reservoir host is the pig.However, other species are also susceptible.Infection with this virus causes a severe neurological clinical picture named Aujeszky’s disease, usually accompanied by itching and death a few days after the onset of sympto

The mucopolysaccharidosis (MPS) disorders are a group of rare, inherited lysosomal storage disorders.In each of the 11 MPS (sub)types, deficiency in a specific lysosomal enzyme (1 of 11 identified enzymes) leads to accumulation of Tweed Caps glycosaminoglycans, resulting in cell, tissue, and multi-organ dysfunction.There is great heterogeneity in t